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Step 6: Inject the solution slowly and steadily

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In pregnant female rats given subcutaneous doses of 0.1, 0.25 and 1.0 mg/kg/day liraglutide from gestation day 6 through weaning or termination of nursing on lactation day 24, estimated systemic exposures were 0.8-, 3-, and 11-times human exposure at the MRHD of 1.8 mg/day, based on plasma AUC

The medication works through the same biological mechanisms at lower doses, but the magnitude and durability of metabolic outcomes at those levels have not been validated in randomized studies