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The cyclic GMPAMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, a key mediator of inflammation, has emerged as a critical mechanism for sensing and regulating the cellular response toward microbial and host-derived DNAs [129]

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Except for patients aged 60 years or above, the improvement in glycemic control due to 5:2 meal replacement was observed across all participants, including obese or overweight patients

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