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Description
The NNT for tirzepatide was 1.23 for achieving 10% weight loss, 1.55 for 15%, 2.07 for 20%, 3.16 for 25%, and 5.08 for 30%
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Clinical evidence supporting the renoprotective effects of incretin receptor agonists primarily derives from large cardiovascular outcome trials, where kidney outcomes were secondary endpoints
Injectable semaglutide is much more sustainable for most patients, especially where several may prefer a once-weekly dose more than a daily pill
People with certain genetic markers may notice changes within 48 hours, while others experience the effect more gradually over one to two weeks
