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A large cohort study found the gastroparesis and pancreatitis risk figures cited above among patients using GLP-1 agonists specifically for weight loss, not diabetes

The goal is personalized, evidence-based therapy that addresses root causes of fatigue or stalled progress rather than adding layers of treatment without clear indication

To help prescribers, ECRIs Clinical Evidence Assessment service recently published a special report on clinical best practices for managing obesity and overweight with GLP-1 receptor agonists

Contact your GP if you experience persistent nausea or vomiting preventing adequate food or fluid intake for more than 24 hours, severe upper abdominal pain (which requires stopping Ozempic and seeking urgent assessment), inability to eat sufficient amounts to maintain nutrition, no appetite suppression after 812 weeks at maintenance dose, or signs of hypoglycaemia if taking insulin or sulphonylureas alongside Ozempic

Theres no one-size-fits-all decision

[DOI] [PubMed] [Google Scholar] 80.Buse JB, Bode BW, Mertens A, Cho YM, Christiansen E, Hertz CL, et al