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Food and Drug Administration) and EMA (European Medicines Agency) have introduced stringent new pharmaceutical packaging requirements to address three critical pillars: Cold-Chain Integrity , Anti-Counterfeiting , and Patient Safety

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ACP defined its clinical guidance as living because it is a priority topic for clinical care and an active area of research, Qaseem and colleagues wrote, and will consider several factors, such as the certainty of the evidence, the balance between benefits and harms, and contextual considerations, when deciding if the guidance will be updated in the future