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Many providers treat tirzepatide as a long-term medication because weight management is often long-term, too

Food and Drug Administration (FDA) approved it in May 2022

GLP-1 receptor agonists and cardiovascular disease: drug-specific or class effects

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The problem is that many people on tirzepatide either do not exercise at all or focus exclusively on cardio

For patients with MCAS specifically, what piqued my interest in giving this class of medications a try was a case series in The American Journal of the Medical Sciences from mast cell experts, including doctors Afrin, Weinstock and Dempsey