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Consistent with these findings, peripherally administered CCK induces cFos immunoreactivity in GLP-1-producing neurons of the hindbrain vagal complex of the NTS [354], and surgical vagal deafferentation reduces CCK-induced NTS neuronal cFos activation by approximately 50% [355]

[DOI] [PMC free article] [PubMed] [Google Scholar] 652.Asmar M., Simonsen L., Arngrim N., Holst J.J., Dela F., Bulow J

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[5] [6] The FLOW trial with semaglutide demonstrated significant reductions in kidney outcomes in patients with type 2 diabetes and chronic kidney disease

Toxicities of opioid analgesics: respiratory depression, histamine release, hemodynamic changes, hypersensitivity, serotonin toxicity