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Some patients tolerate NSAIDs better after completing the dose-escalation phase when GI adaptation is complete

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Mechanisms of Wnt signaling and control

Primarily summarized into 3 main MOA: MOA: Increases Insulin release/sensitivity, decreases glucagon release MOA: Slows gastric emptying (gastric peristalsis) MOA: Appetite Suppression Patho 101: Plasma glucose is maintained by a tug-of-war between the hypoglycemic effect of insulin and the hyperglycaemic effect of glucagon

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Although approval was granted by the Therapeutic Goods Administration (TGA), the manufacturer has not commenced supply of Wegovy to the Australian market