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GLP-1 receptor agonists and high blood pressure often coexist in people with type 2 diabetes, raising important questions about safety and treatment benefits

doi: 10.2337/diabetes.48.12.2270 [DOI] [PubMed] [Google Scholar] 130

As compared to loop diuretics, SGLT2-i may distinctly regulate the interstitial versus intravascular compartment selectively reducing interstitial oedema, which has been observed in HF and DKD, with minimal change in blood volume

Drinking too fast on GLP-1 medications causes the same discomfort as eating too fast

In the United States, it afflicts as many as 40% of adults

Because GLP-1 medications naturally reduce appetite and slow digestion, people often eat less overall