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Female GLP-1RA users showed increased HSV risk (HR=1.51), and poorly controlled patients (HbA1c7%) had higher HSV risks (HR=1.195)

GLP-1 receptor agonists like semaglutide can influence sleep patterns through appetite regulation and metabolic changes

Five scientifically validated bacterial strains cultivate a microbiome environment similar to that of individuals with healthy weight, promoting sustainable weight loss

Despite great progress in GLP-1R structure determination, our understanding on the differences of peptide binding and signal transduction between these two receptors remains elusive

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