tirzepatide surpass-4 SURPASS-4: slows kidney disease in adults with type 2 diabetes, CV risk Tirzepatide Improved Health-Related Quality of
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Early data on an oral semaglutide show daily dosing can achieve about 15% weight loss (versus 23% on placebo), suggesting pill-based GLP-1 therapy can match injections if absorbed properly
Renal function is a key moderator of tirzepatide kinetics

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