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Considerations for Wegovy and Wegovy HD (semaglutide) injection 7.2 mg pen administration 1 : Preparing for injection: Patients should get their supplies together in one place: Theyll need their Wegovy pen, 1 alcohol swab or soap and water, 1 gauze pad or cotton ball, and a sharps disposable container for the used Wegovy pen Wash hands Check the Wegovy pen Do not use the pen if: It appears to have been used Any part appears broken The Wegovy medicine is not clear and colorless through the pen window (air bubbles are normal) The expiration date (EXP) has passed Choosing injection site Help patients choose the injection site that is best for them

The dosing schedule then continues with incremental increases of 2.5 mg after at least four weeks at each dose level, progressing through the following sequence: 2.5 mg once weekly (weeks 1-4): Initial tolerability dose only 5 mg once weekly (weeks 5-8): Minimum therapeutic dose 7.5 mg once weekly (weeks 9-12): Intermediate dose option 10 mg once weekly (weeks 13-16): Higher therapeutic dose 12.5 mg once weekly (weeks 17-20): Higher therapeutic dose 15 mg once weekly (week 21 onward): Maximum approved dose The FDA label specifies that dose escalation should occur after at least four weeks at each dose level, though clinical judgment may warrant extending this timeline if patients experience significant gastrointestinal symptoms

To ensure the best and longest-lasting results, its essential to follow a balanced diet, engage in regular exercise, and avoid significant weight fluctuations