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Clinical trials have shown improvements in A1C, which is a blood test used to measure average blood sugar levels over time

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Moreover, GLP-1R is found in the heart and blood vessels and is beneficial in heart rate, vascular endothelium, atherosclerosis, and hypertension [58, 59]

Nat Rev Dis Primers (2016) 2:16057

For researchers currently building protocols based on Phase 2 data, the Phase 3 dose selection validates the 4mg to 12mg range as the therapeutic window

The consistent reductions in BMI and body weight across various studies highlight the potential of GLP-1RAs in managing PCOS-related conditions, even in populations where metformin has traditionally been the first-line therapy