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Secondly, retatrutide may have released cardiac noradrenaline in the heart to raise the beating rate through cardiac -adrenoceptors

However, unlike Ozempic, Wegovy is FDA-approved for chronic weight management

Common side effects include: Nausea and vomiting Constipation or diarrhea Bloating or indigestion Mild fatigue or dizziness More serious side effects, though less common, can occur

However, the exogenous administration of GLP-1RAs can mitigate sympathetic excitability by suppressing the peripheral chemoreflex originating from the carotid body

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All the GLPs can cause gastrointestinal side effects, from tummy upset, constipation, nausea to diarrhea