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4 The Court held that while the government had a substantial interest in preventing the industrial-scale manufacturing of unapproved drugs, banning the advertisement of truthful information about compounding services was more extensive than necessary

Tirzepatide (a dual GLP-1 and GIP receptor agonist) has a distinct chemical structure and may be better tolerated by people who react to semaglutide alone

In 2025, 24.3% of Americans who had ever taken a GLP-1 reported using a compounded version, and 11% of consumers obtained their GLP-1 medications through online platforms