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Why does hunger come back after GLP-1 treatment

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50 An additional PKA-mediated action of GLP-1R agonists controls -cell gene expression by phosphorylating CREB, a c AMP r esponse e lement- b inding protein

This leads to several effects, like slowing down gastric emptying, i.e

Well have more analysis as we work through the full implications.
The secondary antibodies were anti-mouse (GE Healthcare, Chicago, IL, USA, EUA) and anti-rabbit (Bio-Rad, Des Plaines, IL, USA)