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Perkovic, V., et al

Baylis said losing 40 pounds has given her more energy and makes her feel healthier

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Other potential causes include: Certain medications, including GLP-1 receptor agonists, opioid pain medications, and some antidepressants Previous stomach or abdominal surgery that affects nerves involved in digestion Neurological conditions such as Parkinson's disease or multiple sclerosis Viral infections that temporarily disrupt nerve function Autoimmune disorders that damage nerves or muscles involved in digestion Connective tissue diseases such as scleroderma In some cases, doctors can't identify a specific cause

Furthermore, hormonal signals from the gastrointestinal tract, such as leptin and ghrelin , contribute to the bodys overall energy balance and influence the hypothalamus in modulating hunger and satiety cues