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Description
Clinical trials have demonstrated that participants lost 15-20% of their body weight within 72 weeksa remarkable result indeed

doi:10.1161/01.HYP.31.1.409 77

Specifically, it has been established that 50% to 70% of insulin secretion in response to oral glucose administration is due to the incretin effect [1]

95% CI, 1.18-2.31)
Maintenance is part of the plan

It has been estimated by studies with 1 H-magnetic resonance spectroscopy that decreasing bodyweight by 10% via diet combined with physical activity can induce a reduction in hepatic TG concentration up to nearly 60% in overweight individuals (40)