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Second, while the included studies were all randomized controlled trials, many reported cancer incidences as a secondary or exploratory outcome, potentially leading to underreporting or inconsistent adjudication of events

Started drinking a lot more water and cutting out snacks/ not gettin Down 30lbs in 4 months

GLP-1 and cAMP pathway GLP-1 acts via GLP-1Rs on various tissues, including the pancreas, to increase beta cell insulin synthesis and secretion and decrease alpha cell GCG release

First introduced as a treatment for Type 2 diabetes and now pursued as a blockbuster weight management therapy, GLP-1 receptor agonists (GLP-1 RAs) have ignited a global scale-up effort that is reshaping the drug manufacturing landscape

10.1016/j.hjc.2018.11.008 [DOI] [PubMed] [Google Scholar] 85.Sposito AC, Berwanger O, de Carvalho LSF, Saraiva JFK

Early trial data shows weight loss exceeding 24% at optimal doses, surpassing even tirzepatide