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GLP-1R agonists have been reported to have therapeutic efficacy on several MS animal models and in in vitro models [115,116,117,118]

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Conversely, some patients find that avoiding large meals immediately after injection prevents stomach distension and associated discomfort

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In the GLP1-RA group, three major birth defects comprising one congenital heart defect, one congenital anomaly of the kidney and one case of multiple anomalies were observed, suggesting that these anomalies appear to be aetiologically distinct