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Semaglutide and Tirzepatide for Alcohol Use Disorder This study looked at real-world alcohol consumption behavior among individuals taking semaglutide or tirzepatide, and found dramatic reductions

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The diminished GLP-1 binding of the GLP-1R R380 ECL3 D mutant was partially restored by Asp 15 Glu substitution and almost fully restored by the Asp 15 Lys and inverted Asp 15 Arg substitutions of GLP-1
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