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Do not freeze reconstituted solution, as ice crystal formation can damage the peptide structure

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GLP-1RAs alleviate vascular aging under chronic stress via increasing adiponectin (APN) levels and inhibiting aortic MMP-9 and MMP-2 expression in ApoE -/- mice [96, 149]

Both drug classes have demonstrated ability to increase genioglossus muscle activity, thus preventing upper airway collapse during sleep
