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Other concerning risks include intestinal blockages, pancreatitis, and rare but severe gallbladder complications such as cholecystitis (inflammation)

The FDA-approved maximum dose for weight loss (Wegovy) is 2.4 mg weekly, though clinical practice often caps therapeutic semaglutide at 1.0 to 2.0 mg weekly for compounded formulations

2.2 Patient 2 A 39-year-old female with PWS resulting from mosaic maternal uniparental disomy was evaluated at our Endocrinology Unit

For Heartburn: Antacids: These quickly neutralise stomach acid

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Domperidone, a prokinetic agent that enhances gastric emptying, might seem counterintuitive given Wegovy's mechanism, but it can be prescribed by GPs for nausea when appropriate