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Nonetheless, additional studies are required to directly map CNS drug concentrations to functional outcomes in both animal and human models

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[1] [13] However, according to the Ozempic Summary of Product Characteristics (SmPC), this effect has not been shown to reduce the clinical efficacy of commonly tested medications significantly

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Contribution statement AK and SAA contributed to the concept of the study and study design

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Lancet Diabetes Endocrinol 2019;7:356-67.ArticlePubMed 122

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