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Some research suggests this dual action may enhance weight loss effects compared to GLP-1 alone

Ozempics primary use is not for weight loss but because weight loss is a major side effect, many people have used it as a way to lose weight, putting the drug in high demand and causing shortages for those seeking the medication for diabetic treatment

Phase 3 ACHIEVE-1 trial results for orforglipron, as discussed by Rosenstock and colleagues, demonstrated that this once-daily oral small molecule GLP-1 achieved statistically significant reductions in HbA1c (1.3% to 1.6% from a baseline of 8.0%) compared to placebo in adults with type 2 diabetes

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Ozempic is the brand-name medication for the active ingredient semaglutide, which primarily acts at the GLP-1 receptor alone

While multiple studies have said there is data suggesting benefits from semaglutide, others have also found risks