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Lower the dose or increase the stop interval before major surgery for eGFR 30 to 60, and review renal function tests less than 30 days pre-op
A., Karthikeyan, M., Lackey, M., Villavicencio, D

Salami, an associate professor of urology at the University of Michigan School of Medicine

Dipeptidyl peptidase-4 (DPP-4), also known as CD26, is widely expressed in the epidermis and on multiple immune cell subtypes, and preclinical studies demonstrating cutaneous vasculitis in non-human primates with some, but not all, DPP-4 inhibitors [20], has heightened awareness of the potential consequences of DPP-4 inhibition on the skin

But this is far from certain
