glp-1 receptor agonists should be avoided in patients with Glucagon-like peptide 1 agonists: cardiovascular benefits and mechanisms of action Holding GLP-1 Agonists Prior to
Description
Both tirzepatide and semaglutide come with boxed warnings from the FDA (the strongest safety warning for prescription drugs) about the risk of developing thyroid C-cell tumors

No new data was generated

demonstrated that semaglutide had similar effects in an ovariectomized rat model, increasing -catenin expression and reducing RANKL production, which resulted in a net increase in bone formation

Obesity is no different. When Drucker started in endocrinology in the 1980s, he didnt have many tools to help patients

Do not eat past the point of starting to feel full, as this may cause GI distress

[DOI] [PMC free article] [PubMed] [Google Scholar] 89
