can semaglutide make periods worse Why Your Period Changes on GLP-1s (and When to Be Concerned) — Core Aesthetic Medspa & Weight Loss Clinic How Long Do Semaglutide Side

In the STEP 2 trial, adults with obesity or overweight plus type 2 diabetes lost a mean 9.6% of their body weight at 68 weeks with semaglutide 2.4 mg vs

[DOI] [PMC free article] [PubMed] [Google Scholar] 103.Bharucha AE, Charkoudian N, Andrews CN, Camilleri M, Sletten D, Zinsmeister AR, Low PA

Diarrhea is less common but can occur, especially at higher doses

Since reproductive hormones depend on adequate body fat and energy balance, rapid weight reduction can temporarily shift estrogen and progesterone levels, potentially causing period irregularities

The goal is to provide clear, evidence-informed guidance so patients can make well-supported decisions about their metabolic health

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