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Other medications for high blood pressure, which can increase the effects of beta-blockers Some antidepressants Some drugs for diabetes (including insulin and pills) Medications for asthma, chronic bronchitis, emphysema, or chronic obstructive pulmonary disease (COPD) Allergy shots Antacids that contain aluminum Over-the-counter (OTC) cough, cold, or allergy medicines Beta-Blockers, Alcohol, and Caffeine Beta-Blockers and Pregnancy Tell your doctor if you're pregnant or might become pregnant while taking a beta-blocker