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For additional details and discussion regarding pharmacologic approaches to glycemic management, please refer to the full 2020 ADA Standards of Medical Care
34 These effects are achieved by the expression and translocation of apical glucose transporter type 4 (GLUT4) thus increasing glucose uptake and by the inhibition of pro-apoptotic proteins such as Bad, Bax and FOXO family proteins, thereby improving beta cell survival
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SUSTAIN-6 Investigators
Couzin-Frankel 22 Sept 2023 Barany, Barany)
doi: 10.1056/nejmoa2107519, 20
