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Table 2: Potential Effects of GLP-1 in Arthritis GLP-1 receptor agonists show anti-inflammatory and cartilage-protective effects , though mechanisms are still under investigation

Patent Information: 2026 Novo Nordisk This Instructions for Use has been approved by the U.S

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GLP-1R agonists (e.g., exendin-4 and liraglutide) reduce APP expression and processing in the brains of AD model mice through the activation of GLP-1R, decrease A protein production and plaque aggregation, and thus improve their spatial memory capacity (McClean et al., 2015

The role of AMPK in macrophage metabolism, function and polarisation