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Then, for an additional four weeks, the main groups were resampled to include treatment (Semaglutide, SME, 40 g/kg), or CR, totaling four groups: Control, Model, Model+SME, Model+CR

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The needle is typically electro-polished to remove burrs and is film-coated (lubricated) for patient comfort

Expression of factors involved in adipose metabolism including sterol regulatory element-binding protein (SREBP-1), insulin receptor (IR) and PPAR in liver were measured by RT-PCR and Western blot

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In nutritional ketosis, insulin is present and functioning