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Generic Akkermansia products may use different strains with uncharacterized metabolite profiles
As most discontinuations occurred during the rapid dose-escalation period of treatment, slower up-titration of dose may counter these
As exciting as the effects of GLP-1 drugs are on cancer and heart health, dont sleep on the possibility that pharma companies will eventually test versions of these drugs that are explicitly focused on improving cognitive function
These effects require consistent receptor activation above a threshold that typically corresponds to 1.0 mg or higher weekly doses
Obesity Silver Spring
N Engl J Med 2013;369:14554
