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NCT06015893 Semaglutide Therapy for Alcohol Reduction (STAR) Status: Recruiting This study will test the safety/tolerability and early efficacy of subcutaneous (s.c.) semaglutide at the dose of 2.4 mg/week or maximum tolerated dose (MTD) as a potential new treatment for alcohol use disorder (AUD)

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Compared to the control diet, the ethanol diet resulted in a very significant increase in hepatic steatosis (perilipin 2 staining) and this was significantly less in the GLP-1R agonist-treated ethanol diet group (Fig