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Stimulant-related side effects Many patches contain high doses of natural stimulants (like caffeine, green tea extract, or bitter orange) to try and boost metabolism

[DOI] [PMC free article] [PubMed] [Google Scholar] 130.Villikudathil A.T., Mc Guigan D.H., English A

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When used at the recommended dose and combined with lifestyle changes, they can lead to significant weight loss and improved health

Post-Translational Modifications (PTMs): Many therapeutic peptides undergo PTMs (e.g., amidation, glycosylation) that impact their biological activity
