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Managing Side Effects and Injection Site Reactions Local injection site reactions are generally mild and transient with Wegovy thigh injections

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For those with IBS, the effect is more complex because IBS involves abnormal gut motility and heightened visceral sensitivity, meaning the intestines react more strongly to normal stimuli

Improvements were also noted in waist circumference, blood pressure, fasting glucose, and lipid profiles

In 2025, the FDA approved a convenient oral form known as the Wegovy pill, allowing flexibility based on patient preference

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