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Participants were mostly women (65%), average age 55 years, with mean BMI 39typical of real-world obesity profiles

Conclusions During five years of observation of all persons with T2D in Denmark, use of once-weekly semaglutide independently more than doubled the risk of NAION

In a randomized controlled trial, 52 healthy obese individuals were, after a diet-induced 12% body weight loss, randomized to treatment with or without administration of the GLP-1RA liraglutide (1.2mg per day)
