how were glp 1 agonists discovered Timeline of GLP-1 discovery and clinical development. (a) Key events in Glucagon-like peptide-1 receptor: mechanisms and
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[DOI] [PubMed] [Google Scholar] 44
A healthy gut microbiome with diversity produces short-chain fatty acids, causing GLP-1 release
Gastrointestinal side effects (like nausea, vomiting, and diarrhea) are very common
Amylin, which is also co-secreted with insulin, also affects glucagon release from the -cells
Effect of exenatide on gastric emptying and relationship to postprandial glycemia in type 2 diabetes
V.KirakossianD.DawsonD.DryS
