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These studies demonstrate that there is none or very little GLP-1R expression in the renal vasculature and GLP-1-induced renal artery vasodilation leading to increases in renal blood flow and glomerular filtration rate is diminished in spontaneously hypertensive rats [56, 57]

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Others can move through the early doses more quickly but need more time adjusting to the 8mg to 10mg transition

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SEM Used in Mixed Population (First- or Second-Line Therapy

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