teladoc glp-1 receptor agonists weight management diabetes treatments Drug Savings: A Complete Guide for How to Save on Ozempic, Wegovy, and More GLP-1 for Diabetes vs GLP-1

Description

Incretins are gut secreted hormones, G-protein-coupled receptor peptides, that include glucagon-like peptide 1 (GLP-1), gastric inhibitory polypeptide (GIP) and glucagon (GCG)

Importantly for the availability of coverage across the workforce, the share of firms with 5,000 or more workers covering these medications for weight loss increased significantly over the last year (from 28% in 2024 to 43% in 2025)

Its approval specifically for chronic weight management distinguishes it from many other GLP-1 based medications primarily indicated for diabetes, thereby carving a niche segment focused on the growing global obesity epidemic

For example, in 2021, Employers Health clients that cover AOMs and have prior authorizations spent $0.85 PMPM on obesity products, while those without any restrictions spent $1.08 PMPM

Effect of central administration of GLP-1R analogs on food intake The acute anorectic effect of centrally administered GLP-1 was described simultaneously 1996 by Steve Bloom's group [668] and by Mads Tang-Christensen et al