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Enrolment occurred at 129 sites in 16 countries, including Canada

Plausible mechanisms include weight lossmediated benefit, metabolic regulation and direct antiinflammatory effects, but current data are limited by small samples and uncontrolled designs

Dehydration can affect kidney function, so keeping an eye on creatinine and eGFR levels is a good idea, especially if you have nausea or vomiting
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Dietary modifications are the cornerstone of symptom management: Reduce portion sizes : Eating smaller, more frequent meals prevents overwhelming the already-slowed digestive system
