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Background Despite the effectiveness of glucagon-like peptide-1 agonist (GLP-1A) in the treatment of diabetes, its large molecular weight and high hydrophilicity result in poor cellular permeability, thus limiting its oral bioavailability

WHAT'S INCLUDED

The combination of IV bimagrumab and subcutaneous semaglutide was linked to large reductions in body weight and fat mass at 72 weeks with no serious impact on lean mass, according to the results of the BELIEVE trial.For BELIEVE, presented at the American Diabetes Association Scientific Sessions, researchers randomly assigned 507 patients with obesity to one of nine arms: placebo;

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