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American Journal of Medicine , 135(12), 1454-1464
Parallel fibrogenesis in the liver and myocardium adds to ventricular stiffness and diastolic dysfunction, while gut dysbiosis from a Western diet heightens systemic inflammation and endotoxemia, worsening cardiac and hepatic dysfunction
This action slows gastric emptying, enhances feelings of fullness, and reduces overall appetite, which leads to decreased calorie intake
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When functioning properly, GLP-1 makes it easier to eat less and feel full on smaller portions
