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Laurie Mbuntum (Cardiology fellow, UTSW) join Dr

A recent study investigated the effects of GLP-1R agonists in a multi-hit mouse model in which the combination of a high-fat diet and angiotensin II-induced a cardiometabolic HFpEF phenotype that resembles the human HFpEF phenotype to a large extent characterized by obesity, impaired glucose handling, and metabolic dysregulation accompanied by inflammation

On first sight, this could indicate that there is no principal barrier for endogenous GLP1 to reach at least this part of the brain, though it would require a large enough dose to overcome the physiological inactivation of the native, gutderived GLP1 in the circulation

The program is designed for adults 18 and older who meet standard GLP-1 prescribing eligibility criteria - typically BMI 30 or higher, or BMI 27 or higher with at least one qualifying weight-related condition (such as hypertension, type 2 diabetes, dyslipidemia, or sleep apnea)

This pricing structure removes the financial barrier to finding your optimal dose without worrying about escalating costs

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