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In the second case, a 40-year-old woman with a history of depression reported worsening mood symptoms, including fatigue, cognitive slowing, and suicidal thoughts, approximately two months after beginning semaglutide for diabetes management

Theres a key similarity across both nations: its the more affluent demographic that is using GLP-1s the most

[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Naylor J., Suckow A.T., Seth A., Baker D.J., Sermadiras I., Ravn P., Howes R., Li J., Snaith M.R., Coghlan M.P., et al

The strongest direct evidence here is for retatrutide alone (Phase 2 and Phase 3 trial data)

Baseline Lp(a) level was the strongest predictor of response: higher starting Lp(a) led to larger absolutereductions, while the percentage reduction remained relatively constant across Lp(a) levels