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FDA is acknowledging that the drugs dont have the same risk seen with older weight-loss medicines

So when someone says, GLP-1s cause muscle loss, the first question should be: what exactly was measured

GLP-1 drugs such as Ozempic are accelerating interest in protein to address the loss of lean muscle mass that can accompany rapid weight loss.

Time-to-onset analysis revealed a median latency of 32 days (IQR 7122) for GLP-1 RA-related NAEs, with 45.28% occurring within 30 days of treatment initiation
Adipokines (e.g., leptin and adiponectin) are regulated by DPP-4 and may influence bone remodeling and energy metabolism in a paracrine manner
fewer (1 in 2) people 65 and older felt the drugs were effective for them
