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However, up to 89% of participants taking efinopegdutide experienced gastrointestinal adverse events (mostly nausea, vomiting and diarrhoea) relative to 28% taking placebo and 60% taking liraglutide (86)

Early research suggests they may alter microbial composition through changes in motility and bile acid metabolism

Patients should be educated about DKA symptoms (nausea, vomiting, abdominal pain, excessive thirst, frequent urination, fatigue, fruity-scented breath) and when to seek urgent care

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Therapeutic peptides: technological advances driving peptides into development