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The problem is straightforward: more weight loss means more physiological stress, and more physiological stress means a stronger trigger for hair shedding

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H2 receptor blockers: Similar to PPIs, medications like famotidine and ranitidine reduce gastric acid and can impair dietary B12 absorption

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Diabetic retinopathy and serious allergic reactions Rapid improvement in glucose control can temporarily worsen diabetic retinopathy in some patients

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Mistake 5: stopping and restarting without guidance Taking an unplanned break from tirzepatide, whether because of a supply issue, travel, or a decision to "take a week off," and then restarting without any dose adjustment is a common mistake

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Early CVOTs on GLP-1RAs, such as the LEADER, Harmony Outcomes, REWIND, and SUSTAIN-6 trials, focused on patients with T2DM and demonstrated the cardioprotective effects of these agents, including liraglutide, albiglutide, dulaglutide, and semaglutide.[811] The potential cardiovascular benefits of GLP-1RAs in patients without diabetes remain an active area of research

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