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J Am Heart Assoc 12(11):e029282 Labouesse MA, Stadlbauer U, Weber E, Arnold M, Langhans W, Pacheco-Lpez G (2012) Vagal afferents mediate early satiation and prevent flavour avoidance learning in response to intraperitoneally infused exendin-4

28 Regulating immune signaling pathways prevents inflammatory cytokines such as tumor necrosis factor-alpha (TNF-) and interleukin-6 (IL-6) from producing and releasing

On average, studies show most people living with obesity lose between 15% and 25% of their body weight after just one year on a GLP-1

doi: 10.1111/jdi.12466 [DOI] [PMC free article] [PubMed] [Google Scholar] 19

The ACC also supports the use of GLP-1R agonists for cardiovascular risk reduction in patients with T2DM and multiple ASCVD risk factors, independent of glucose control or background antihyperglycemic therapy [122]

But in humans it can be used to suppress our pain pathway