changing from tirzepatide to retatrutide vs (2026): Differences in Weight Loss, Metabol – Revolution Health & Wellness Switching From Tirzepatide to Retatrutide

Effective July 1, 2025, AOM tirzepatide (sold as Zepbound) was removed from its standard preferred formulary ( 9 )

However, achieving optimal results requires adherence to the recommended doses

Some researchers combine their tirzepatide protocol with other compounds

For a 100kg individual, that translates to 22.5kg lost versus 2.4kg

Percent change in weight from baseline to week 72 Primary outcome: Results Among participants with obesity but without diabetes, treatment with tirzepatide was superior to treatment with semaglutide with respect to reduction in body weight and waist circumference at week 72

The key difference may be in the magnitude of caloric deficit